Current Research

UF Radiation OncologyOne of the great benefits of receiving cancer care at an academic health center is that our clinician-scientists participate in cutting-edge research. In addition to multi-institutional clinical trial groups, the Radiation Oncology Department is involved in in-house protocols (sets of instructions for treatment, or treatment plans) that are used at the University of Florida. Some involve only the Radiation Oncology Department; many others represent joint effort by two or more departments. Most of these protocols are considered “standard of care”, but some are investigational.

To learn more about clinical studies, visit our Clinical Studies pages. To browse our collection of published research by UF Radiation Oncologists, visit our NCBI bibliography.

Recent Faculty Publications

Please note that some may be in process.

Robert Amdur, MD

  1. Challenging the concept that late recurrence and death from tumor are common after fractionated radiotherapy for benign meningioma. O’steen L, Amdur RJ, Morris CG, Mendenhall WM. Radiother Oncol. 2019 May 6;137:55-60. doi: 10.1016/j.radonc.2019.04.017. [Epub ahead of print]
    PMID: 31071515 [PubMed – as supplied by publisher]
  2. The High Number of Unfilled Positions in the 2019 Radiation Oncology Residency Match: Temporary Variation or Indicator of Important Change? Bates JE, Amdur RJ, Lee WR. Pract Radiat Oncol. 2019 May 14. pii: S1879-8500(19)30126-2. doi: 10.1016/j.prro.2019.05.001. [Epub ahead of print] No abstract available.
    PMID: 31100471 [PubMed – as supplied by publisher]
  3. Regarding “patient-reported versus physiologic swallowing outcomes in patients with head and neck cancer after chemoradiation”.  Amdur RJ, Chera BS. Laryngoscope. 2019 May;129(5):E169. doi: 10.1002/lary.27862. Epub 2019 Feb 13. No abstract available.  PMID: 30761549 [PubMed – indexed for MEDLINE]

Julie Bradley, MD

  1. Predicting parental distress among children newly diagnosed with craniopharyngioma. Peterson RK, Ashford JM, Scott SM, Wang F, Zhang H, Bradley JA, Merchant TE, Conklin HM. Pediatr Blood Cancer. 2018 Oct;65(10):e27287. doi: 10.1002/pbc.27287. Epub 2018 Jun 22. PMID: 29932288 [PubMed – indexed for MEDLINE]
    2. Esophagitis associated with multimodality management of pediatric Ewing sarcoma of thorax. Agarwal V, Logie N, Morris CG, Bradley JA, Rotondo RL, Bradfield SM, Indelicato DJ. Pediatr Blood Cancer. 2018 Jun;65(6):e27006. doi: 10.1002/pbc.27006. Epub 2018 Feb 12. PMID: 29431250 [PubMed – indexed for MEDLINE]
    3. Early outcomes and patterns of failure following proton therapy for nonmetastatic intracranial nongerminomatous germ cell tumors. Mokhtech M, Rotondo RL, Bradley JA, Sandler ES, Nanda R, Logie N, Aldana PR, Morris CG, Indelicato DJ. Pediatr Blood Cancer. 2018 Jun;65(6):e26997. doi: 10.1002/pbc.26997. Epub 2018 Jan 30. PMID: 29380526 [PubMed – indexed for MEDLINE]
    4. A comprehensive dosimetric study of Monte Carlo and pencil-beam algorithms on intensity-modulated proton therapy for breast cancer. Liang X, Li Z, Zheng D, Bradley JA, Rutenberg M, Mendenhall N. J Appl Clin Med Phys. 2019 Jan;20(1):128-136. doi: 10.1002/acm2.12497. Epub 2018 Nov 28. PMID: 30488548 [PubMed – indexed for MEDLINE] Free PMC Article

Roi Dagan, MD, MS

Rapid Clearance Profile of Plasma Circulating Tumor HPV Type 16 DNA during Chemoradiotherapy Correlates with Disease Control in HPV-Associated Oropharyngeal Cancer. Chera BS, Kumar S, Beaty BT, Marron D, Jefferys SR, Green RL, Goldman EC, Amdur R, Sheets N, Dagan R, Hayes DN, Weiss J, Grilley-Olson JE, Zanation AM, Hackman TG, Blumberg JM, Patel S, Weissler MC, Tan X, Parker JS, Mendenhall WM, Gupta GP. Clin Cancer Res. 2019 May 14. pii: clincanres.0211.2019. doi: 10.1158/1078-0432.CCR-19-0211. [Epub ahead of print] PMID: 31088830 [PubMed – as supplied by publisher]

Daniel Indelicato, MD

  1. Esophagitis associated with multimodality management of pediatric Ewing sarcoma of thorax.  Agarwal V, Logie N, Morris CG, Bradley JA, Rotondo RL, Bradfield SM, Indelicato DJ. Pediatr Blood Cancer. 2018 Jun;65(6):e27006. doi: 10.1002/pbc.27006. Epub 2018 Feb 12. PMID: 29431250 [PubMed – indexed for MEDLINE]
  2. Early outcomes and patterns of failure following proton therapy for nonmetastatic intracranial nongerminomatous germ cell tumors. Mokhtech M, Rotondo RL, Bradley JA, Sandler ES, Nanda R, Logie N, Aldana PR, Morris CG, Indelicato DJ. Pediatr Blood Cancer. 2018 Jun;65(6):e26997. doi: 10.1002/pbc.26997. Epub 2018 Jan 30. PMID: 29380526 [PubMed – indexed for MEDLINE]

Zuofeng Li, DSc

A comprehensive dosimetric study of Monte Carlo and pencil-beam algorithms on intensity-modulated proton therapy for breast cancer.  Liang X, Li Z, Zheng D, Bradley JA, Rutenberg M, Mendenhall N. J Appl Clin Med Phys. 2019 Jan;20(1):128-136. doi: 10.1002/acm2.12497. Epub 2018 Nov 28. PMID: 30488548 [PubMed – indexed for MEDLINE] Free PMC Article

Nancy Mendenhall, MD

Conventional Radiation Therapy Compared With Stereotactic Conformal Therapy-A Rare and Laudable Randomized Trial.  Mendenhall NP, Fitzgerald TJ. JAMA Oncol. 2017 Oct 1;3(10):1376-1377. doi: 10.1001/jamaoncol.2017.1552. No abstract available. PMID: 28570720 [PubMed – indexed for MEDLINE]

William Mendenhall, MD

  1. Challenging the concept that late recurrence and death from tumor are common after fractionated radiotherapy for benign meningioma. O’steen L, Amdur RJ, Morris CG, Mendenhall WM. Radiother Oncol. 2019 May 6;137:55-60. doi: 10.1016/j.radonc.2019.04.017. [Epub ahead of print] PMID: 31071515 [PubMed – as supplied by publisher]
  2. Rapid Clearance Profile of Plasma Circulating Tumor HPV Type 16 DNA during Chemoradiotherapy Correlates with Disease Control in HPV-Associated Oropharyngeal Cancer. Chera BS, Kumar S, Beaty BT, Marron D, Jefferys SR, Green RL, Goldman EC, Amdur R, Sheets N, Dagan R, Hayes DN, Weiss J, Grilley-Olson JE, Zanation AM, Hackman TG, Blumberg JM, Patel S, Weissler MC, Tan X, Parker JS, Mendenhall WM, Gupta GP. Clin Cancer Res. 2019 May 14. pii: clincanres.0211.2019. doi: 10.1158/1078-0432.CCR-19-0211. [Epub ahead of print] PMID: 31088830 [PubMed – as supplied by publisher]
  3. Primary orbital melanoma treated with orbital exenteration and postoperative radiotherapy: A case report and review of the literature.  Haskins CP, Nurkic S, Fredenburg KM, Dziegielewski PT, Mendenhall WM. Head Neck. 2018 Mar;40(3):E17-E20. doi: 10.1002/hed.24983. Epub 2018 Feb 2. Review. PMID: 29394463 [PubMed – indexed for MEDLINE]

Lori Rice, PhD

Reliability of blood lactate as a measure of exercise intensity in different strains of mice during forced treadmill running. Lønbro S, Wiggins JM, Wittenborn T, Elming PB, Rice L, Pampo C, Lee JA, Siemann DW, Horsman MR. PLoS One. 2019 May 3;14(5):e0215584. doi: 10.1371/journal.pone.0215584. eCollection 2019. PMID: 31050686 [PubMed – in process] Free Article

Ronny Rotondo, MD

  1. Esophagitis associated with multimodality management of pediatric Ewing sarcoma of thorax.  Agarwal V, Logie N, Morris CG, Bradley JA, Rotondo RL, Bradfield SM, Indelicato DJ. Pediatr Blood Cancer. 2018 Jun;65(6):e27006. doi: 10.1002/pbc.27006. Epub 2018 Feb 12. PMID: 29431250 [PubMed – indexed for MEDLINE] Similar articles
  2. Early outcomes and patterns of failure following proton therapy for nonmetastatic intracranial nongerminomatous germ cell tumors. Mokhtech M, Rotondo RL, Bradley JA, Sandler ES, Nanda R, Logie N, Aldana PR, Morris CG, Indelicato DJ. Pediatr Blood Cancer. 2018 Jun;65(6):e26997. doi: 10.1002/pbc.26997. Epub 2018 Jan 30. PMID: 29380526 [PubMed – indexed for MEDLINE]

Dietmar Siemann, PhD

  1. Reliability of blood lactate as a measure of exercise intensity in different strains of mice during forced treadmill running. Lønbro S, Wiggins JM, Wittenborn T, Elming PB, Rice L, Pampo C, Lee JA, Siemann DW, Horsman MR. PLoS One. 2019 May 3;14(5):e0215584. doi: 10.1371/journal.pone.0215584. eCollection 2019. PMID: 31050686 [PubMed – in process] Free Article
  2. Axl signaling is an important mediator of tumor angiogenesis.  Tanaka M, Siemann DW. Oncotarget. 2019 Apr 23;10(30):2887-2898. doi: 10.18632/oncotarget.26882. eCollection 2019 Apr 23. PMID: 31080559 [PubMed] Free PMC Article
  3. Prostate cancer cell growth characteristics in serum and prostate-conditioned media from moderate-intensity exercise-trained healthy and tumor-bearing rats. Opoku-Acheampong AB, Baumfalk DR, Horn AG, Kunkel ON, Ganta CK, McCullough DJ, Siemann DW, Muller-Delp J, Behnke BJ. Am J Cancer Res. 2019 Apr 1;9(4):650-667. eCollection 2019. PMID: 31105994 [PubMed] Free PMC Article

Sadasivan Vidyasagar, MBBS, PhD

Intestinal DMT1 Is Essential for Optimal Assimilation of Dietary Copper in Male and Female Mice with Iron-Deficiency Anemia. Wang X, Flores SR, Ha JH, Doguer C, Woloshun RR, Xiang P, Grosche A, Vidyasagar S, Collins JF. J Nutr. 2018 Aug 1;148(8):1244-1252. doi: 10.1093/jn/nxy111. PMID: 30137476 [PubMed – indexed for MEDLINE]

Anamaria Yeung, MD

Expanded validation of the EPIC bowel and urinary domains for use in women with gynecologic cancer undergoing postoperative radiotherapy.  Gil KM, Pugh SL, Klopp AH, Yeung AR, Wenzel L, Westin SN, Gaffney DK, Small W Jr, Thompson S, Doncals DE, Cantuaria GHC, Yaremko BP, Chang A, Kundapur V, Mohan DS, Haas ML, Kim YB, Ferguson CL, Deshmukh S, Kachnic LA, Bruner DW. Gynecol Oncol. 2019 May 16. pii: S0090-8258(19)31184-9. doi: 10.1016/j.ygyno.2019.04.682. [Epub ahead of print] PMID: 31104905 [PubMed – as supplied by publisher]