Restenosis is typically defined as a renarrowing of an arterial blood vessel within six months of an angioplasty, CABG, or other vascular procedure.  It  typically occurs in approximately 25% to 45% of patients, and is the result of an excessive  response to arterial injury after a revascularization procedure. Restenosis may occur within a short period after a  procedure or may develop over the course of months or years.

Longer term or ” late” restenosis may result from excessive proliferation of scar tissue at the treatment site, the causes of which are not well understood.

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