UF Research Team Creates Next Generation Oral Rehydration Solution

Sadasivan Vidyasagar, Department of Radiation Oncology, University of Florida College of MedicineA research team led by Sadasivan Vidyasagar, MBBS, PhD, UF Radiation Oncology Professor, has created an Oral Rehydration Solution that increases electrolyte and fluid absorption in the presence of cholera toxin, decreases epithelial anion channel activity, and improves intestinal barrier function.

This formulation by Dr. Vidyasagar (right) and his team will now undergo testing in clinical trials for validation as a new treatment option in patients with infectious diarrhea. Dr. Vidyasagar is founder of Entrinsic Bioscience, a UF startup and an alumnus of UF Innovate | Accelerate.

The findings were presented at a Plenary Session during Digestive Disease Week (May 6-9), Chicago, in a talk titled “Select Amino Acids (AA-ORS) Improve Electrolyte and Fluid Absorption in a Rodent Diarrhea Model”.


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